Substance P stimulates differentiation of mice osteoblast through up-regulating Osterix expression.
Posted on January 31st, 2010 in Stem Cell Therapy, Stem Cells
Conclusions: SP can up-regulate Osterix gene expression to stimulate differentiation of mesenchymal stem cells into osteoblastic cells at the final stage. The regulatory effect of SP on Osterix expression was dependant on SP NK1 receptors.
PMID: 20109368 [PubMed - in process] (Source: Chinese Journal of Traumatology)
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