Authors: Y Tian, B Guo, H Jia, K Ji, Y Sun, Y Li, T Zhao, L Gao, Y Meng, D V Kalvakolanu, D J Kopecko, X Zhao, L Zhang & D Xu (Source: Cancer Gene Therapy) MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to [...]
Use of gene therapy for heart failure is gaining momentum as a result of the recent successful completion of phase II of the Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) trial, which showed clinical safety and efficacy of an adeno?associated viral vector expressing sarco?endoplasmic reticulum calcium ATPase (SERCA2a). Resorting to [...]
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
In this study, we found that miR-145 was significantly under-expressed in osteosarcoma tissues, and the over-expression of miR-145 could inhibit invasion and angiopoiesis of osteosarcoma cells. Furthermore, the results showed that vascular endothelial growth factor (VEGF) expression was down-regulated in osteosarcoma cells after miR-145 transfection. On the basis of these results, we performed the luciferase [...]
Conclusion SERCA2a gene therapy of failing hearts restores miR-1 expression by an Akt/FoxO3A-dependent pathway, which is associated with normalized NCX1 expression and improved cardiac function. (Source: European Heart Journal)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
(University of Pennsylvania School of Medicine) HIV patients treated with genetically modified T cells remain healthy up to 11 years after initial therapy, researchers from the Perelman School of Medicine at the University of Pennsylvania report in the new issue of Science Translational Medicine. The results provide a framework for the use of this type [...]
Patients doing well a decade later but virus itself not eradicated (Source: Pharmacy News – Doctors Lounge)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
HIV patients treated with genetically modified T cells remain healthy up to 11 years after initial therapy, researchers report. The results provide a framework for the use of this type of gene therapy as a powerful weapon in the treatment of HIV, cancer, and a wide variety of other diseases. (Source: ScienceDaily Headlines)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Patients doing well a decade later but virus itself not eradicated (Source: Cancercompass News: Other Cancer) MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Adoptive cell therapy with tumor-targeted T cells is a promising approach to cancer therapy. Enhanced clinical outcome using this approach requires conditioning regimens with total body irradiation, lymphodepleting chemotherapy, and/or additional cytokine support. However, the need for prior conditioning precludes optimal application of this approach to a significant number of cancer patients intolerant to these [...]
Authors: I M Barbash, S Cecchini, A Z Faranesh, T Virag, L Li, Y Yang, R F Hoyt, J N Kornegay, J R Bogan, L Garcia, R J Lederman & R M Kotin (Source: Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Authors: J C M van der Loo, W P Swaney, E Grassman, A Terwilliger, T Higashimoto, A Schambach, S Hacein-Bey-Abina, D L Nordling, M Cavazzana-Calvoo, A J Thrasher, D A Williams, L Reeves & P Malik (Source: Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Title: Study: Gene Therapy for HIV Safe, But Effectiveness Still UnclearCategory: Health NewsCreated: 5/2/2012 4:05:00 PMLast Editorial Review: 5/3/2012 12:00:00 AM (Source: MedicineNet HIV General)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
By Ewen Callaway of Nature magazine [More] Source:http://rss.sciam.com/sciam/topic/gene-therapy
Authors: Yokoi F, Dang MT, Li Y Abstract Early-onset generalized torsion dystonia (dystonia 1) is an inherited movement disorder caused by mutations in DYT1 (TOR1A), which codes for torsinA. Most patients have a 3-base pair deletion (?GAG) in one allele of DYT1, corresponding to a loss of a glutamic acid residue (?E) in the C-terminal [...]
This study clearly shows that in vivo approaches have the potential to address fundamental questions on the cellular mechanisms regulating gene delivery. Content Type Journal ArticleCategory Original PaperPages 1-13DOI 10.1007/s00418-012-0959-7Authors Monika Sramkova, Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive [...]
The Advances news section in April's issue of Scientific American included stories on digital textbooks, the promise of using gene therapy to fight blindness and how fragile orchids survive. To learn more about any of the stories, follow these links. [More] Source:http://rss.sciam.com/sciam/topic/gene-therapy
After several years of setbacks, gene therapy is once again yielding promising results. One area in which it is proving its potential is in restoring vision to patients who have been losing it since birth. [More] Source:http://rss.sciam.com/sciam/topic/gene-therapy
The American Society of Gene & Cell Therapy is pleased to honor Dr. David Williams, MD, as the recipient of the Outstanding Achievement Award at the Society’s 15th Annual Meeting on Saturday, May 19th.Milwaukee, WI (PRWEB) May 04, 2012 Pioneering researcher recognized for scientific achievements in gene and cell therapyThe American Society of Gene & Cell Therapy is pleased to honor Dr
By Randy Dotinga HealthDay Reporter WEDNESDAY, May 2 (HealthDay News) — New research shows that gene therapy can have long-lasting effects on the immune cells of HIV patients — a promising sign — even though the specific treatment being studied did not eradicate the virus. This approach is one of several gene therapy strategies that are being investigated by scientists as possible ways to keep the AIDS virus from spreading in the blood. In this case, “people were treated by gene therapy and nothing bad happened
