StemCells Therapy

33054641 story Posted by Soulskill on Tuesday May 15, @08:17PM from the boosterspice-before-i-get-old-please dept. Grond writes “ScienceDaily reports, ‘Researchers at the Spanish National Cancer Research Centre have demonstrated that the mouse lifespan can be extended by the application in adult life of a single treatment acting directly on the animal’s genes.

Researchers in Spain may have discovered the secret to a longer life, a new study says.

ScienceDaily (May 14, 2012) A new study consisting of inducing cells to express telomerase, the enzyme which — metaphorically — slows down the biological clock — was successful.

Gene therapy has been used to increase the lifespan of mice by up to 24 percent – and improve their health at the same time. Telomerase helps to maintain the physical integrity of the ends of chromosomes. And mice that received a single treatment to deliver the enzyme to different cells in the body showed drastic improvements in health, fitness and longevity, says the team.

Washington, May 15 (ANI): Scientists have successfully extended the lifespan of mice using gene therapy, a strategy never before employed to combat ageing.

Conclusions: The present study demonstrated for the first time the potential antitumor activity of IFN-alpha combined with the oncolytic adenovirus SG600-IL-24 in HCC both in vitro and in vivo, and suggests its further development as a potential candidate for HCC cancer gene therapy. (Source: Molecular Cancer)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

Gene therapy protects body while leaving cancer cells vulnerable (Source: ScienceNOW)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

The immunodeficiency disorder Wiskott-Aldrich syndrome (WAS) leads to life-threatening hematopoietic cell dysfunction. We used WAS protein (WASp)–deficient mice to analyze the in vivo efficacy of lentiviral (LV) vectors using either a viral-derived promoter, MND, or the human proximal WAS promoter (WS1.6) for human WASp expression. Transplantation of stem cells transduced with MND-huWASp LV resulted in [...]

Conclusions The new NGS approach delivers a step change in the diagnosis of inherited eye disease, provides precise diagnostic information and extends the possibility of targeted treatments including gene therapy. The approach represents an exemplar that illustrates the opportunity that NGS provides for broadening the availability of genetic testing. The technology will be applied to [...]

The study involved painstaking molecular analysis of blood samples taken annually from the patients, who participated in separate studies begun in 2000, 2002, and 2004. “We were astonished that we could detect the modified cells for so long.

Public release date: 11-May-2012 [ | E-mail | Share ] Contact: Quinn Eastman qeastma@emory.edu 404-727-3990 Emory University Regenerating sensory hair cells, which produce electrical signals in response to vibrations within the inner ear, could form the basis for treating age- or trauma-related hearing loss. One way to do this could be with gene therapy that drives new sensory hair cells to grow.

Todays post is a repost from October 2010. Ive got some major stuff cooking in the lab right now and I need all of my brain power for it. Enjoy the repost and I shall return! Reader David sent me this paper the other day, and asked if I could blog about it.

The three stories in the half-hour QUEST TV show Pump It Up: Heart Health Special Report investigate the number one cause of death in America, heart disease, which kills 600,000 people each year – more than die from cancer, car accidents or AIDS. We look at the disease from the point of view of a [...]

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(MedPage Today) — A gene therapy approach to HIV treatment is long-lasting and safe, researchers reported. (Source: MedPage Today Infectious Disease) MedWorm Sponsor Message: Please have a look at this new site driven by MedWorm: The Breast Cancer Daily Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

Authors: H Shen, T Sun & M Ferrari (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

Authors: B Thaci, A U Ahmed, I V Ulasov, A L Tobias, Y Han, K S Aboody & M S Lesniak (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

Interferon-β lipofection II. Mechanisms involved in cell death and bystander effect induced by cationic lipid-mediated interferon-β gene transfer to human tumor cells Cancer Gene Therapy advance online publication, May 4, 2012. doi:10.1038/cgt.2012.19 Authors: M S Villaverde, M L Gil-Cardeza, G C Glikin & L M E Finocchiaro (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

Authors: P B Card, R T Hogg, C R Gil del Alcazar & R D Gerard (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml