Researchers have been able to see how heart failure affects the surface of an individual heart muscle cell in minute detail, using a new nanoscale scanning technique. The findings may lead to better design of beta-blockers, the drugs that can slow the development of heart failure, and to improvements in current therapeutic approaches to treating [...]
Conclusions: Latent gammaherpesvirus infection augments subsequent fibrotic responses in mice. Enhanced fibrosis is associated with the induction of profibrotic factors and the recruitment of fibrocytes. Our data complement existing human and animal data supporting the hypothesis that gammaherpesviruses can serve as initiating cofactors in the pathogenesis of pulmonary fibrosis.
PMID: 20185751 [PubMed [...]
The scientist and TV presenter tells us why it’s important to check out the dark side of inventions firstRobert Winston, Professor of Science and Society and Emeritus Professor of Fertility Studies at Imperial College, London, is one of the best-known popularisers of science in this country and has a reputation for taking a provocative stance [...]
If you (or someone you know) has metastatic cancer of the lung, prostate, colon, rectum, kidney, pancreas or malignant melanoma that is not responding to standard treatments, you may be able to participate in our clinical trial designed to evaluate the safety of a new type of cell therapy. Specifically, we are testing the safety [...]
A routine interview question asked by a famous consulting firm is “Sell me the middle seat on an airplane.” It’s a great question– who can conjure up any value in that pariah of a seat? Some answer, “It’s the last seat on the plane– take it or leave it.” Others say, “You’re only one seat [...]
In this study we set out to test the hypothesis that the Hp genotype regulates the turnover and oxidative activity of Hb in the atherosclerotic plaque. (Source: Atherosclerosis)
Authors: Fournier C, Tisman G
Psoriasis is a disease characterized by epidermal hyperproliferation that results in the formation of lesional plaques covered by scale. Psoriasis is thought to be angiogenesis dependent. Clear cell renal cell carcinoma is a hypervascularized solid tumor associated with loss of function of the von Hippel-Lindau (VHL) tumor [...]
Authors: Suzuki Y, Nakamura-Wakatsuki T, Satoh M, Nishibu A, Kawakami Y, Oyama N, Yamamoto T
PMID: 20178711 [PubMed - in process] (Source: Dermatol Online J)
MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed – updated hourly from thousands of authoritative health and news [...]
Authors: Jilani G, Mohamed D, Wadia H, Ramzi K, Meriem J, Houssem L, Samir G, Nawfel BR
A 39-year-old man, who had undergone left nephrectomy for renal cell carcinoma of clear cell type, was noted to have a solitary nodular shadow in the right lung on chest X-ray. Percutaneous needle biopsy of [...]
Authors: Dubey S, Sharma R, Maheshwari V
Scrotal calcinosis is a rare benign local process characterized by multiple, painless, hard scrotal nodules in the absence of any systemic metabolic disorder. Histological examination reveals extensive deposition of calcium in the dermis, which may be surrounded by histiocytes and an inflammatory giant cell reaction. [...]
Authors: Ghorab MM, Ragab FA, Heiba HI, Youssef HA, Galal M
Several novel pyrazole (11-18) and pyrimidine (19-23) derivatives were synthesized starting from different sulfonamides and different active methylenes. The synthesized compounds were characterized by elemental analysis, IR, 1H-NMR and mass spectral data. The obtained compounds were screened as antitumor agents against [...]
Monte Carlo simulations were performed to extend existing neutron personal dose equivalent fluence-to-dose conversion coefficients to an energy of 250 MeV. Presently, conversion coefficients, Hp,slab(10,)/, are given by ICRP-74 and ICRU-57 for a range of angles of radiation incidence ( = 0, 15, 30, 45, 60 and 75°) in the energy range from thermal to [...]
Shire plc (LSE: SHP, Nasdaq: SHPGY), the global specialty biopharmaceutical company, announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for VPRIV, a human cell line derived enzyme replacement therapy (ERT) for the long-term treatment of Type 1 Gaucher disease in pediatric and adult patients… (Source: Pharma Industry News From Medical [...]
Programs to create a new center for the study of stem cells and to increase capacity to deal with global health issues were among seven scientific initiatives announced by NIH Director Francis S. Collins, M.D., Ph.D. The seven research programs are supported through the NIH Common Fund, which encourages collaborative research programs across the NIH [...]
Librede Inc. has joined the UCLA on-campus technology incubator space at the California NanoSystems Institute, where the startup company will work on developing technologies to improve ion channel drug discovery and screening. Ion channels are proteins in cell membranes that play a central role in generating and transmitting cardiac and neural signals. The channels control [...]
A few days back, Salesforce.com, the famous cloud computing company , announced the Beta program of Social Neworking tool for Enterprises, Social Chatter. The software will be available during the calendar year of 2010. Customers will be able to access Chatter’s real time feed anytime and anyplace through iPhone or Blackberry. Companies are having a hard [...]
LONDON – US troops are to be allowed to use social networking websites such as Twitter and Facebook following a review of internet use and security.
The BBC quotes defence department officials as saying that the benefits of using social media now [...]
Using TigerText, user can set a time limit about the text message to stay after it is read. When the limit exceeded, the message will disappear from the recipient’s phone, the sender’s phone and any servers. After this, you can not forward the message to anywhere, store the message or sold it to a flashy [...]
Tumor initiation via loss of cell contact inhibition versus Ras mutation: Do all roads lead to EMT? [FriendFeed entry][Connotea bookmark][PubMed citation] http://bit.ly/bIYZjW
CD133+ cells are more resistant to anticancer drugs than CD133- cells in neuroblastoma cell lines [FriendFeed entry][Connotea bookmark][PubMed citation] http://bit.ly/bCJKkI
Breast cancer chemoresistance: Emerging importance of CSC [FriendFeed entry][ResearchGATE entry][PubMed citation] http://bit.ly/cmgfj4
Neoplastic [...]
Sap’s rising: Sweet money for maple syrup hobby
IRA, Vt. — Eric May wasn’t too keen on the taste of real maple syrup when he first moved to Vermont but he tapped some trees anyway, borrowing buckets from neighboring farmers. After boiling the sap for 18 hours in a pot over an outside fire, he produced [...]