StemCells Therapy

Sky broadcasts world’s first live 3-D sports event
LONDON — British pub-goers became the first public audiences to witness a live sports event broadcast in 3-D when watching Manchester United beat Arsenal 3-1.
Nine pubs across Britain were equipped to screen the first 3-D transmission by Sky Sports on Sunday.
Previous trials have been limited to closed-circuit broadcasts [...]

Scientists discuss in ‘Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines’ new findings in osteosarcoma. According to a study from the United States, Insulin-like growth factor-I receptor (IGF-IR) is an important mediator of tumor cell survival and shows prognostic significance in sarcoma. (Source: [...]

Conclusions: Apoptosis and expressions of bax and bcl-2 in lung tissues might be involved in the pathogenesis of lung injury induced by blunt chest trauma. Penehyclidine hydrochloride can alleviate lung injuries by inhibiting apoptosis of lung tissue cells, during which effects of penehyclidine hydrochloride on regulating expressions of bax and bcl-2 may play an important [...]

Conclusions: SP can up-regulate Osterix gene expression to stimulate differentiation of mesenchymal stem cells into osteoblastic cells at the final stage. The regulatory effect of SP on Osterix expression was dependant on SP NK1 receptors.
PMID: 20109368 [PubMed - in process] (Source: Chinese Journal of Traumatology)

Authors: Wang ET, Zhao M
Endogenous electric fields (EFs) have been detected at wounds and damaged tissues. The potential roles of EFs in tissue repair and regeneration have been an intriguing topic for centuries. Recent researches have provided significant insights into how naturally occurring EFs may participate in the control of tissue [...]

Hydrolysis-resistant surface attachment upgrades photoelectrochemical cell (Source: Nanotechweb.org journal highlights)

ACE inhibitors may reduce foam-cell formation triggered by oxidized low-density lipoprotein by affecting the activity of matrix metalloproteinase-9, research suggests. (Source: MedWire News – Lipidology)

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Yue Li, Guang-Kui Xu, Bo Li, and Xi-Qiao Feng Cell spreading on an extracellular matrix is crucial for many biological functions and processes. By accounting for the molecular mechanisms of actin polymerization and integrin binding between the cell and the extracellular matrix, we here propose a biophysical model to predict the time-dependent g … [Appl. [...]

Mahmut Selman Sakar, Edward B. Steager, Dal Hyung Kim, Min Jun Kim, George J. Pappas et al. For biomedical applications, such as single cell manipulation, it is important to fabricate microstructures that can be powered and controlled wirelessly in fluidic environments. In this letter, we describe the construction and operation of truly micron-sized, biocompatible ferromagnetic [...]

A paracoccidioidomicose é uma micose sistêmica causada pelo fungo dimórfico Paracoccidioides brasiliensis. A doença é restrita à América Latina. É a principal micose sistêmica no Brasil, com maior frequência nas regiões sul, sudeste e centro-oeste. A doença é adquirida através da inalação de propágulos do fungo. Nas áreas endêmicas, a infecção primária ocorre durante a [...]

We report the case of an oil industry worker diagnosed with hard metal lung disease. The diagnosis was based on the clinical, radiological and anatomopathological analysis, as well as on pulmonary function testing. (Source: Jornal Brasileiro de Pneumologia)

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DNA and Cell Biology , Vol. 0, No. 0. (Source: DNA and Cell Biology)

Tandon Prakash NNeurology India 2009 57(6):706-714The nearly absent ability of the neurons to regenerate or multiply has prompted neuroscientists to search for the mean to replace damaged or dead cells. The failed attempts using adult tissue, initiated nearly a century ago, ultimately brought rays of hope when developing fetal neurons were used for transplantation in [...]

Conclusions</b> : Epo exerts neuroprotective effect against traumatic brain injury via reducing Bax gene expression involved in inhibiting TBI-induced neuronal cell death. (Source: Neurology India)

There have been several reports of patients with two hematopoietic neoplasms, one showing B-cell differentiation and the other being a histiocytic (H) or dendritic cell (DC) sarcoma (). It is intriguing that the two neoplasms have been found to be clonally related in all cases with clonality studies reported. We recently evaluated a patient who [...]

Chronic myeloid leukemia (CML) is a clonally hematologic malignant disease arising in the stem-cell compartment. Patients with CML show considerable heterogeneity both in their presenting clinical features and in the time taken for evolution to blast crisis . Herein we report the unusual case of a patient with Ph chromosome-positive CML who achieved complete hematological [...]

Lymphoplasmacytic lymphoma (LPL) is a lymphoproliferative disorder which usually has an indolent course . We recently observed a leukemic form of LPL with a very aggressive clinical course and with massive skin infiltration. A 44-year-old woman was under observation because of malaise and fatigue as result of a moderate pancytopenia. She presented with pallor and [...]

Micafungin, which is the class of echinocandin antifungal drugs that inhibit ?-(1,3)-d-glucan synthesis that is the main composition element of fungal cell walls in the peculiarity and has an excellent antimycotic activity, possesses high effectiveness against invasive aspergillosis and Candida spp., it excels also in safety, and it is used for the management of fungal [...]

We report a case of C-ALCL presenting with hemophagocytic syndrome and skin lesion with giant ulcer. Histopathological examination of the skin biopsy specimens showed non-epidermotropic infiltrates with cohesive sheets of large tumor cells. The tumor cells showed CD4?, CD8+, CD30+, CD56?, ALK?, TIA-1+, and granzyme B+. C-ALCL is generally a disorder that progresses slowly and [...]

Abstract: Nucleophosmin 1 (NPM1), a protein that shuttles between the nucleus and cytoplasm, is mostly located in nucleoli. This is a multifunctional phosphoprotein to which both tumor-suppressor and oncogenic functions have been attributed. Here, we have found the cell line with the type A NPM1 mutation and with the other genetic alterations including ETV6-NTRC fusion. [...]